Broadening the horizons for yellow fever: new uses for an old vaccine
نویسنده
چکیده
The yellow fever vaccine has already been used with great success to create vaccines against yellow fever’s close relatives, the RNA-based flaviviruses. Recent successes with other yellow fever– based vaccines, combined with increased interest in the basic immunology of the virus, provide new hope that this nearly century-old vaccine vector may provide the basis for protecting against not just flaviviruses but also unrelated pathogens for which effective vaccines have yet to be developed.
منابع مشابه
Broadening the horizons for yellow fever
The vaccine against yellow fever is one of the safest and most effective ever developed. With an outstanding record in humans, has this live attenuated vaccine been overlooked as a promising vector for the development of vaccines against pathogens outside its own genus? Recent studies, including a report by Tao et al. on page 201 of this issue, have sparked renewed interest.
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متن کاملiMedPub Journals ARCHIVES OF CLINICAL MICROBIOLOGY
Title: Multi-system organ failure following administration of yellow fever vaccine: a case report Background: Yellow fever vaccine-associated viscerotropic disease (YEL-AVD), is an extremely rare and life-threatening condition that occurs shortly after administration of the vaccine. It is characterized by multi-system organ failure including hemorrhagic fever, shock, renal failure, and hepatic ...
متن کاملInfant meningoencephalitis caused by yellow fever vaccine virus transmitted via breastmilk.
OBJECTIVE To describe a case of infant meningoencephalitis that was probably caused by yellow fever vaccine virus transmitted via breastmilk. DESCRIPTION A 38-day old patient was admitted to hospital on May 23, 2009, with fever. On May 25, 2009, convulsive crises began. Cerebrospinal fluid (CSF) test results were suggestive of meningoencephalitis. The mother had been given a dose of yellow fe...
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تاریخ انتشار 2005